Nguyen Thanh Tam, Nguyen Ngoc Tuan, Hoang Van Trung, Le Thi My Chau, Dinh Thi Trung Anh, Hoang Van Luu


Abstract HCTN_12

A phytochemical study of extracts of Uvaria boniana Fin. & Gagnep collected at Vũ Quang National park, Nghe An province leaves led to the isolation of five secondary metabolites, including uvaridacol G (1); 4-methyl-4-[(2Z)-3’-phenylprop-2’-en-1’-yl]cyclohex-2-en-1-one (2); 3,7- dimethoxy quercetin 4’- O- [α-L- rhamnopyranosyl-(12) -β-D- glucopyranoside (3); b-sitosterol (4) and stigmasterol (5). Their structure elucidation were determined on the basis of one and two-dimensional NMR and spectrometric methods in combination with molecular modeling. This is the first report on the chemical constituents of Vietnamese Uvaria boniana.


Uvaria boniana, metabolites, uvaridacol G, 3,7- dimethoxy quercetin 4’- O- [α-L- rhamnopyranosyl- (1 2) -β-D- glucopyranoside

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Parmar V.S., Tyagi O.D., Malhotra A., Singh S.K., Bisht K.S. and Jain R. - , Nat. Prod. Rep. 11, 219 (1994).

Liu A., Xu L.Z., Z.M. Zou and Yang S.L. - Foreign Med. Sci. 23, 195 (2001).

Chantrapromma K., Pakawatchai C., Skelton B. W., White A. H. and Worapatamasri S. - 5 -Hydroxy-7-methoxy-2-phenyl-4H-1 -benzopyran-4-one (tectochrysin) and 2, 5- dihydroxy-7-methoxy-2-phenyl-2, 3-dihydro-4H-1 - benzopyran-4-one: Isolation from Uvaria rufas and X-ray structures, Aust. J. Chem. 42 (1989) 2289-2293.

Deepralard K., Kawanishi K., Moriyasu M., Pengsuparp T. and Suttisri R. - Flavonoid glycosides from the leaves of Uvaria rufa with advanced glycation end-products inhibitory activity, Thai J. Pharm. Sci. 33 (2009) 84-90.

Macabeo A.P.G., Tudla F.A., Alejandro G.J.D., Kouam S.F., Hussain H. and Krohn K.. - Benzoylated derivatives from Uvaria rufa, Biochem. Syst. Ecol. 38 (2010) 857–860.

Brophy J. and Goldsack R. - Essential oils from the leaves of some Queensland Annonaceae, J. Essent. Oil Res. 16 (2004) 95–100.

Tudla F.A., Aguinaldo A.M., Krohn K., Hussain H. and Macabeo A.P.G. - Highly oxygenated cyclohexene metabolites from Uvaria rufa, Biochem. Syst. Ecol. 35 (2007) 45-47.

Zhang C.R., Yang S.P., Liao S.G., Wu Y. and Yue J.M. - Polyoxygenated cyclohexene derivatives from Uvaria rufa, Helv. Chim. Acta 89 (2006) 1408-1416.

Burkill I.H.H. - A dictionary of the economic products of the malay peninsular. Volume II. Governments of Malaysia and Singapore by the Ministry of Agriculture and Co-operatives. Kuala Lumpur, (1966) 2255-2257.

Gimlette J.D. - A Dictionary of Malayan Medicine, Oxford University Press, (1971) 141.

Suresh A., Ueda J., Athikomkulchai S., Dibwe D. F., Yokoyama S.A.S., Saiki I. and Ryuta Miyatake - Uvaridacols E − H, Highly oxygenated antiausterity agents from Uvaria dac, 75(11) 1999-2002.

Dictionary of Natural product on CD-Rom (2009), Chapman and Hall-CRC.

Sinz A., Matusch R., Santisuk T., Chaichana S., Reutrakul V. - Flavonol glycosides from Dasymaschalon sootepense, Phytochemistry 47(7) (1998) 1393-1396.

Kuo H. Y. and Yeh M. H. - Chemical constituents of heartwood of Bauhinia purpurea L., J. Chin. Chem. Soc. 44 (1997) 379-383.

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