Antifungal, antibacterial and cytotoxic activities of some Ardisia species from Vietnam

Trinh Anh Vien, Nguyen Thi Hong Van, Do Thi Thao, Tran Thi Nhu Hang, Nguyen Anh Tuan, Pham Quoc Long


Methanol extracts of nine species of the genus Ardisia from Vietnam were screened for antifungal, antibacterial and cytotoxic activities. The obtained results showed that the methanol extract of A. incarnata exhibited the strongest cytotoxic activity against all five tested cancer cell lines with IC50 values ​​ranging from 5.26 to 8.46 mg/ml, and resisted A. niger with the MIC value 200 mg/ml. The methanol extracts of A. balansana, A. caudata, A. insularis, A. pseudocrispa, A. splendens have moderate cytotoxic and antimicrobial activities. The methanol extracts of A. maculosa, A. tsangii, A. primulifolia did not show cytotoxic and antimicrobial activities.


Ardisia, antimicrobial activity, antifungal activity, cytotoxic activity

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