Megastigmans and other compounds from Antidesma hainanensis Merr.

Le Canh Viet Cuong, Do Thi Trang, Nguyen Xuan Nhiem, Pham Hai Yen, Bui Huu Tai, Hoang Le Tuan Anh, Le Mai Huong, Chau Van Minh, Phan Van Kiem


Four megastigmans 7-megastigmene-3-ol-9-one 3-O-[α-L-arabinofuranosyl-(1→6)-β-D-glucopyranoside]  (1),  alangionoside L (2),  alangioside (3), ampelopsisionoside (4), and other constituents as N–trans-feruloyloctopamide (5), trans-linalool-3,6-oxide-β-D-glucopyranoside (6),  5α,8α-dipioxiergosta-6,22-diene-3β-ol (7), and (Z)-2-hexenyl β-D-glucopyranoside (8) were isolated from the methanol extract of the Antidesma hainanensis leaves. Their chemical structures were successfully determined using NMR and ESI-MS analysis as well as in comparison with the reported data. This is the first report of these compounds from Euphorbiaceae family.


Antidesma hainanensis, Euphorbiaceae, megastigman.

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