Steroids from the blood cockle Anadara granosa

Phan Thi Thanh Huong, Nguyen Hoang Giang, Tran Thi Hong Hanh, Do Cong Thung, Nguyen Xuan Cuong, Nguyen Van Thanh, Chau Van Minh


Using various chromatographic experiments, four sterols as 5α,8α-epidioxy-24(S)-ethylcholest-6-en-3β-ol (1), (22E,24S)-5α,8α-epidioxy-24-ethyl-cholesta-6,22-dien-3β-ol (2), 7-oxocholesterol (3), and (22E)-3β-hydroxycholesta-5,22-dien-7-one (4) were isolated from the methanol extract of the blood cockle Anadara granosa. The structures of isolated compounds were elucidated by 1D and 2D-NMR experiments in comparison with reported data. This is the first report of these compounds from A. granosa.


Anadara granosa, Arcidae, blood cockle, steroid.

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