Merosesquiterpenes from marine sponge Smenospongia cerebriformis

Le Thi Huyen, Dan Thi Thuy Hang, Nguyen Xuan Nhiem, Bui Huu Tai, Hoang Le Tuan Anh, Pham Hai Yen, Nguyen Van Dau, Chau Van Minh, Phan Van Kiem


Using various chromatography methods, three merosesquiterpenes belonging to sesquiterpene quinone type, neodactyloquinone (1), dactyloquinone D (2), and dactyloquinone C (3) together with two indole derivatives indole-3-aldehyde (4) and indole-3-cacboxylic methyl ester (5) were isolated from the methanol extract of the Vietnamese marine sponge Smenospongia cerebriformis. Their structures were determined by 1D-, 2D-NMR spectra, HR-ESI-MS and in comparison with those reported in the literature.

Keywords. Smenospongia cerebriformis, merosesquiterpene, sesquiterpene quinone, indole derivative.


Smenospongia cerebriformis, merosesquiterpene, sesquiterpene quinone, indole derivative.

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