Silychristin and isosilychristin from the fruits of Silybum marianum (L.) Gaertin

Trinh Thi Diep, Phan Van Kiem, Nguyen Thuong Dong, Nguyen Huu Tung, Bui Thi Bang, Chau Van Minh, Alessandra Braca


By various chromatography methods, two flavonolignan silychristin (1) and isosilychristin (2)were isolated from the fruits of Silybum marianum (L.) Gaertn. cultivated in the North of Vietnam. Their structures were elucidated by analyses of the NMR (1D-, 2D-NMR) and ESI spectra. This is the first report of both 1 and 2 from S. marianum cultivated in Vietnam.

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