Secondary metabolites from Micromonospora ectrinospora G017

Vu Thi Quyen, Truong Bich Ngan, Doan Thi Mai Huong, Marie-Lise Bourguet Kondracki, Arlette Longeon, Brian Murphy Murphy, Chau Van Minh, Pham Van Cuong


Eight  compounds, cyclo-(Pro-Tryp) (1), N-[2-(1H-indol-3-yl)-2-oxo-ethyl] acetamide (2), cyclo-(Pro-Tyr) (3), cyclo-(Pro-Phe) (4), cyclo-trans-4-OH-(Pro-Phe) (5), cyclo-(Pro-Leu) (6), cyclo-(Pro-Val) (7), and  uracil (8) were isolated from the culture broth of the marine Micromonospora ectrinospora G017 strain. The structures of the isolated compounds were established on the basis of their spectral data, including mass spectrometry and NMR.


Micromonospora ectrinospora G017 strain, cyclo-(Pro-Tryp), N-[2-(1H-Indol-3-yl)-2-oxo-ethyl] acetamide, cyclo-(Pro-Tyr), cyclo-(Pro-Phe), cyclo-trans-4-OH-(Pro-Phe), cyclo-(Pro-Leu), cyclo-(Pro-Val), uracil

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