Chinh Thuy Nguyen, Mai Thi Tran, Manh Quoc Vu, Tran Thi Thu Nguyen, Trang Do Mai Tran, Trung Quoc Vu, Hang Van Ha, Hoang Thai



Collagen from fish is attracting a lot of attention thanks to its high absorbance ability, biocompatibility as well as non-religious obstruction and cheap sources. It could be applied in many fields, for example: food, cosmetic, or biomedicine. Using of collagen also helps to reduce the environment pollution from fish scale waste in fish processing. In this study, collagen extracted from Vietnamese fresh-water tilapia fish scales was used in combination with carrageenan for the improvement of drug release control. The influence of fish scale collagen content on morphology, thermal behavior and drug release from carrageenan/collagen/allopurinol composite film was evaluated by methods such as field emission scanning electron microscopy (FESEM), differential scanning calorimetric (DSC) and ultraviolet-visible spectroscopy (UV-Vis). From the DSC data, FESEM analysis and drug release of carrageenan/collagen/allopurinol composite films, the most suitable collagen in composite film is 5 wt.%.


Fish scale collagen, drug release, carrageenan and biomedicine.

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DOI: https://doi.org/10.15625/2525-2518/57/3B/14044 Display counter: Abstract : 522 views. PDF : 165 views.


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