Antibacterial, antioxidant and xanthine oxidase inhibitiory activities of extracts from some lichen species of families flavoparmelia and flavopunctelia
Keywords:Anntibacterial, free radical scavenging activity, reducing power, xanthine oxidase.
This study evaluates antibacterial activities of extracts of Flavoparmelia caperata (L.) Hale, Flavoparmelia baltimorensis (Gyelnik & Foriss) Hale, Flavopunctelia soredica (Nyl.) Hale and Flavopunctelia flaventior (Stirton) Hale by disc-diffusion methods against three gram positive and three gram negative bacteria. The solvents used as extractants in this study were acetone. The antibacterial activities of lichen extracts were comparable with Ampicilline, commonly used antibiotics for the treatment of infections. Antibacterial activities of lichen extracts ranged from 6.67-22 mm. It was observed from the studies that the most resistant bacteria was gram negative bacteria and the most sensitive bacteria was Enterococcus faecalis, Salmonella enterica. Of the lichens tested, Flavoparmelia caperata had highest free radical scavenging activity (IC50=0.791 mg/mL). Moreover, the strong relationships between total phenolic and flavonoid contents and the antioxidant effect of tested extracts were observed. All extracts were found to be strong in inhibitory activity of xanthine oxidase with IC50 values ranging from 39.24 to 275.6 μg/mL.