Study on antibiotics activity in vitro and treatment effects in place in the experimental burns of EB product isolated from the rhizome of Eleutherine bulbosa

Authors

  • Nguyen Thi Hong Van VAST
  • Do Thi Nguyet Que
  • Nguyen Thu Hang VAST
  • Le Thi Loan VAST
  • Luu Tuan Anh VAST
  • Nguyen Van Hoan

DOI:

https://doi.org/10.15625/0866-7160/v36n1.4523

Keywords:

Bacillus, Eleutherine bulbosa, Proteus, Shigella, Staphylococcus aureus, antibacterial activity

Abstract

The products EB containing of eleutherine and isoeleutherine have been extracted from the rhizome of Eleutherine bulbosa and showed the antibacterial effect on experimental animals. Based on the results of diameter of sterile ring using the agar diffusion method, EB products have a significant antibacterial effect against Bacillus subtilis, Staphylococcus aureus, Shigella flexneri DT 112, Proteus mirabilis BV 108 and Bacillus pumilus at concentrations of 50 μg/ml and 100 μg/ml. The EB products exhibited also their antibacterial activity in vivo on the experimental thermal burn in the rabbit skin, reducing the density of bacterial/cm2 at 7 days after treatment by EB ointment, these antibacterial effect of EB is equivalent to sulfadiazine - 1% silver.

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Published

23-08-2014

How to Cite

Hong Van, N. T., Nguyet Que, D. T., Hang, N. T., Loan, L. T., Anh, L. T., & Hoan, N. V. (2014). Study on antibiotics activity in vitro and treatment effects in place in the experimental burns of EB product isolated from the rhizome of Eleutherine bulbosa. Academia Journal of Biology, 36(1), 81–87. https://doi.org/10.15625/0866-7160/v36n1.4523

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